COVID-19 VACCINE LETHAL INJECTIONS

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Moderna
COVID-19 Vaccine

(Moderna, USA)

The Official Story

MODERNA COVID-19 VACCINE
(Moderna, USA)

The Moderna COVID 19 vaccine, sold under the brand name Spikevax, is a COVID-19 vaccine developed by American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA). Depending on the jurisdiction, it is authorized for use in people aged six months, twelve years, or eighteen years and older. It provides protection against COVID-19 which is caused by infection by the SARS-CoV-2 virus. It is designed to be administered as two or three 0.5 mL doses given by intramuscular injection at an interval of at least 28 days apart.

It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles.

It is authorized for use at some level in many countries.

In August and September 2022, bivalent versions of the vaccine (Moderna COVID-19 Vaccine, Bivalent) containing elasomeran/elasomeran 0-omicron (Spikevax Bivalent Zero/Omicron) were authorized for use as booster doses in individuals aged 18 years of age or older in the United Kingdom, Switzerland, Australia, Canada, the European Union, and the United States. The second component of the version of the bivalent vaccine used in the United States (mRNA-1273.222) is based on the Omicron BA.4/BA.5 variant, while the second component in the bivalent vaccine version used in other countries (mRNA-1273.214) is based on the Omicron BA.1 variant.

Pharmacology

Moderna’s technology uses a nucleoside-modified messenger RNA (modRNA) compound codenamed mRNA-1273. The mRNA-1273 drug delivery system uses a PEGylated lipid nanoparticle drug delivery (LNP) system. Once the compound is inside a human cell, the mRNA links up with the cell’s endoplasmic reticulum. The mRNA-1273 is encoded to trigger the cell into making a specific protein using the cell’s normal manufacturing process. The vaccine encodes a version of the spike protein with a modification called 2P, in which the protein includes two stabilizing mutations in which the original amino acids are replaced with prolines, developed by researchers at the University of Texas at Austin and the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center. Once the protein is expelled from the cell, it is eventually detected by the immune system, which begins generating efficacious antibodies.

Authorizations

Expedited

As of December 2020, the Moderna COVID 19 vaccine was under evaluation for emergency authorization or approval by multiple countries which would enable rapid rollout of the vaccine in the United Kingdom, the European Union (EU), Canada, and the United States.

On 18 December 2020, the Moderna COVID 19 vaccine was authorized by the US Food and Drug Administration (FDA) under an emergency use authorization (EUA) for people aged 18 years of age and older. This is the first product from Moderna that has been authorized by the FDA. In June 2022, the EUA was expanded to include people aged six months through sixteen years of age.

On 23 December 2020, the Moderna COVID 19 vaccine was authorized by Health Canada.

On 5 January 2021, the Moderna COVID 19 vaccine was authorized for use in Israel by its Ministry of Health.

On 3 February 2021, the Moderna COVID 19 vaccine was authorized for use in Singapore by its Health Sciences Authority.

On 30 April 2021, the World Health Organization (WHO) granted emergency use listing.

On 5 May 2021, the Moderna COVID 19 vaccine was authorized for emergency use in the Philippines by the Philippines Food and Drug Administration.

In 2020, Moderna partnered with Takeda Pharmaceutical Company, and the Japan Ministry of Health, Labour and Welfare (MHLW). The vaccine is known as “COVID-19 Vaccine Moderna Intramuscular Injection”. On 21 May 2021, COVID 19 Vaccine Moderna Intramuscular Injection (formerly TAK-919) was authorized for emergency use in Japan.

On 29 June 2021, the Moderna COVID 19 vaccine was authorized for use in India by the Drugs Controller General of India. The same day, the vaccine was also approved by the Ministry of Health of Vietnam for emergency use in the country.

On 5 August 2021, Malaysia’s National Pharmaceutical Regulatory Agency (NPRA) gave conditional registration for emergency use of the Moderna COVID 19 vaccine.

Source: Wikipedia

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Moderna COVID-19 Vaccine

The Moderna COVID-19 vaccine, also known as Spikevax, is an mRNA vaccine produced by the American company Moderna, the U.S. National Institute of Allergy and Infectious Diseases, the U.S. Biomedical Advanced Research and Development Authority, and the Coalition for Epidemic Preparedness Innovations. The Moderna vaccine is not offered for men under 30 years of age in Finland as a precaution to reduce a very rare risk of myocarditis.

Moderna Worldwide Authorizations

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Original

Full (5)

Emergency (116)

Emergency (EMA countries)

Emergency (CARPHA countries)

Non-country entities

American Samoa
Anguilla
Aruba
Bermuda
British Virgin Islands
Caribbean Netherlands
Cayman Islands
Curaçao
Faroe Islands
Greenland
Guadeloupe
Guam
Guernsey
Isle of Man
Jersey
Montserrat
Northern Mariana Islands
Puerto Rico
Sint Maarten
Turks and Caicos Islands
Wallis and Futuna
World Health Organization

Travel-only

Hong Kong
New Zealand
Turkey

Bivalent original–BA.1

EMA countries

Bivalent original–BA.4/5

United States

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